Comparison of Tacrolimus Intra-Patient Variability during 6–12 Months after Kidney Transplantation between CYP3A5 Expressers and Nonexpressers

Comparison of Tacrolimus Intra-Patient Variability during 6–12 Months after Kidney Transplantation between CYP3A5 Expressers and Nonexpressers

A high intra-patient variability (IPV) of tacrolimus exposure is associated with poor long-term kidney transplantation outcomes. To assess the influence of <i>cytochrome P450 (CYP) 3A5</i> genetic polymorphisms on tacrolimus IPV, 188 clinically stable kidney transplant recipients, who ha...

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Bibliographic Details
Main Authors: Almas Nuchjumroon, Somratai Vadcharavivad, Wanchana Singhan, Manorom Poosoonthornsri, Wiwat Chancharoenthana, Suwasin Udomkarnjananun, Natavudh Townamchai, Yingyos Avihingsanon, Kearkiat Praditpornsilpa, Somchai Eiam-Ong
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Journal of Clinical Medicine
Subjects:
CYP3A5
genetic polymorphism
immunosuppression
intra-patient variability
kidney transplantation
tacrolimus
Online Access:https://www.mdpi.com/2077-0383/11/21/6320

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https://www.mdpi.com/2077-0383/11/21/6320

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