Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease

Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an accepted treatment for motor symptoms in a subset of Parkinson's disease (PD) patients. The mechanisms why DBS is effective are incompletely understood, but previous studies show that DBS targeted in brain structures ot...

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Bibliographic Details
Main Authors: Ilse S. Pienaar, Cecilia Heyne Lee, Joanna L. Elson, Louisa McGuinness, Stephen M. Gentleman, Raj N. Kalaria, David T. Dexter
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Neurobiology of Disease
Subjects:
Deep-brain stimulation
Growth factor
Parkinson's disease
Subthalamic nucleus
Tight junction proteins
Vasculature
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114003775

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http://www.sciencedirect.com/science/article/pii/S0969996114003775

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