Optimizing Lutetium 177–Anti–Carbonic Anhydrase IX Radioimmunotherapy in an Intraperitoneal Clear Cell Renal Cell Carcinoma Xenograft Model

A new approach in the treatment of clear cell renal carcinoma (ccRCC) is radioimmunotherapy (RIT) using anti-carbonic anhydrase IX (CAIX) antibody G250. To investigate the potential of RIT with lutetium 177 ( 177 Lu)-labeled G250, we conducted a protein dose escalation study and subsequently an RIT...

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Bibliographic Details
Main Authors: Constantijn H.J. Muselaers, Egbert Oosterwijk, Desirée L. Bos, Wim J.G. Oyen, Peter F.A. Mulders, Otto C. Boerman
Format: Article
Language:English
Published: SAGE Publishing 2014-06-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2014.00008