Crocetin Mitigates Irradiation Injury in an In Vitro Model of the Pubertal Testis: Focus on Biological Effects and Molecular Mechanisms

Crocetin Mitigates Irradiation Injury in an In Vitro Model of the Pubertal Testis: Focus on Biological Effects and Molecular Mechanisms

Infertility is a potential side effect of radiotherapy and significantly affects the quality of life for adolescent cancer survivors. Very few studies have addressed in pubertal models the mechanistic events that could be targeted to provide protection from gonadotoxicity and data on potential radio...

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Bibliographic Details
Main Authors: Giulia Rossi, Martina Placidi, Chiara Castellini, Francesco Rea, Settimio D'Andrea, Gonzalo Luis Alonso, Giovanni Luca Gravina, Carla Tatone, Giovanna Di Emidio, Anna Maria D’Alessandro
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
saffron
crocetin
pubertal testis
X-rays
radiotherapy
fertility preservation
Online Access:https://www.mdpi.com/1420-3049/26/6/1676

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https://www.mdpi.com/1420-3049/26/6/1676

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