Sodium thiosulfate ameliorates oxidative stress and preserves renal function in hyperoxaluric rats.

BACKGROUND: Hyperoxaluria causes crystal deposition in the kidney, which leads to oxidative stress and to injury and damage of the renal epithelium. Sodium thiosulfate (STS, Na2S2O3) is an anti-oxidant, which has been used in human medicine for decades. The effect of STS on hyperoxaluria-induced ren...

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Bibliographic Details
Main Authors: Rakesh K Bijarnia, Matthias Bachtler, Prakash G Chandak, Harry van Goor, Andreas Pasch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4415920?pdf=render