Dual role of Apolipoprotein D as long-term instructive factor and acute signal conditioning microglial secretory and phagocytic responses

Dual role of Apolipoprotein D as long-term instructive factor and acute signal conditioning microglial secretory and phagocytic responses

Microglial cells are recognized as very dynamic brain cells, screening the environment and sensitive to signals from all other cell types in health and disease. Apolipoprotein D (ApoD), a lipid-binding protein of the Lipocalin family, is required for nervous system optimal function and proper develo...

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Bibliographic Details
Main Authors: Miriam Corraliza-Gomez, Beatriz Bendito, David Sandonis-Camarero, Jorge Mondejar-Duran, Miguel Villa, Marta Poncela, Jorge Valero, Diego Sanchez, Maria D. Ganfornina
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
microglia
cytokine secretion
myelin phagocytosis
amyloid-beta endocytosis
membrane-binding protein
immune memory
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1112930/full

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https://www.frontiersin.org/articles/10.3389/fncel.2023.1112930/full

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