Mitochondrial calcium signaling and redox homeostasis in cardiac health and disease

The energy demand of cardiomyocytes changes continuously in response to variations in cardiac workload. Cardiac excitation-contraction coupling is fueled primarily by adenosine triphosphate (ATP) production by oxidative phosphorylation in mitochondria. The rate of mitochondrial oxidative metabolism...

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Bibliographic Details
Main Authors: Tudor-Alexandru Popoiu, Christoph Maack, Edoardo Bertero
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Molecular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmmed.2023.1235188/full