Renin-angiotensin-system increases phosphorylated tau and Reactive Oxygen Species in human cortical neuron cell line

Renin-angiotensin-system increases phosphorylated tau and Reactive Oxygen Species in human cortical neuron cell line

Alzheimer's Disease (AD) is the most common cause of dementia. AD patients had increased extracellular amyloid β plaques and intracellular hyperphosphorylated tau (p-tau) in neurons. Recent studies have shown an association between the Renin-Angiotensin System (RAS) and AD. The involvement of R...

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Bibliographic Details
Main Authors: Luz De Dios, Camille Collazo, Yaritza Inostroza-Nieves
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Renin-angiotensin-system
Angiotensin II
Losartan
Alzheimer's disease
Cortical neurons
Tau phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822001558

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http://www.sciencedirect.com/science/article/pii/S2405580822001558

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