Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso.

Besides existing artemisinin-based combination therapies, alternative safe, effective and affordable drug combinations against falciparum malaria are needed. Methylene blue (MB) was the first synthetic antimalarial drug ever used, and recent studies have been promising with regard to its revival in...

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Main Authors: Augustin Zoungrana, Boubacar Coulibaly, Ali Sié, Ingeborg Walter-Sack, Frank P Mockenhaupt, Bocar Kouyaté, R Heiner Schirmer, Christina Klose, Ulrich Mansmann, Peter Meissner, Olaf Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2238815?pdf=render