Sestrin2 protects against hypoxic nerve injury by regulating mitophagy through SESN2/AMPK pathway

Sestrin2 protects against hypoxic nerve injury by regulating mitophagy through SESN2/AMPK pathway

Hypoxia induced by high altitude can lead to severe neurological dysfunction. Mitophagy is known to play a crucial role in hypoxic nerve injury. However, the regulatory mechanism of mitophagy during this injury remains unclear. Recent studies have highlighted the role of Sestrin2 (SESN2), an evoluti...

Full description

Bibliographic Details
Main Authors: Cunyao Pan, Chongyi Ai, Lanlan Liang, Baoyi Zhang, Qionglin Li, Lingling Pu, Zirou Wang, Weili Liu, Zhaoli Chen, Hui Liu, Xinxing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
hypoxia
mitophagy
SESN2
AMPK
FUNDC1
neurological dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1266243/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1266243/full

Similar Items