Enhancing human capillary tube network assembly and maturation through upregulated expression of pericyte-derived TIMP-3

In this study, we identify and characterize new molecular determinants that optimize human capillary tube network assembly. Our lab has previously reported a novel, serum free-defined 3D co-culture model using human endothelial cells (ECs) and human pericytes whereby EC-lined tubes form and co-assem...

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Bibliographic Details
Main Authors: Ksenia Yrigoin, Kaitlyn N. Bernard, Maria A. Castaño, Ondine Cleaver, Saulius Sumanas, George E. Davis
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1465806/full