Distribution of polymorphic genotypes of GSTP1, GSTM1 and GSTT1 and their association with primary open-angle glaucoma

Background: The role of genetic factors in the development of primary open-angle glaucoma (POAG) has been confirmed previously. Activation of oxidative stress with a reduction in the activity of glutathione S transferase (GST) family enzymes is a major mechanism in the pathogenesis of POAG. Since th...

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Bibliographic Details
Main Authors: S.O. Rykov, A.V. Burdei, S.V. Ziablitsev, S.Iu. Mogilevskyy
Format: Article
Language:English
Published: Ukrainian Society of Ophthalmologists 2018-06-01
Series:Journal of Ophthalmology
Subjects:
Online Access:https://www.ozhurnal.com/en/archive/2018/3/6-fulltext