The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells

The molecular organization of exocytic vesicles regulates their transport and fusion. Prasai, Taraska, and colleagues use correlative light and electron microscopy, along with 3D tomography and gold labeling, to directly map proteins on single exocytic organelles at the plasma membrane.

Bibliographic Details
Main Authors: Bijeta Prasai, Gideon J. Haber, Marie-Paule Strub, Regina Ahn, John A. Ciemniecki, Kem A. Sochacki, Justin W. Taraska
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24167-9