Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs

Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs

The PSD-95/SAPAP/Shank complex functions as the major scaffold in orchestrating the formation and plasticity of the post-synaptic densities (PSDs). We previously demonstrated that the exquisitely specific SAPAP/Shank interaction is critical for Shank synaptic targeting and Shank-mediated synaptogene...

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Bibliographic Details
Main Authors: Jinwei Zhu, Qingqing Zhou, Yuan Shang, Hao Li, Mengjuan Peng, Xiao Ke, Zhuangfeng Weng, Rongguang Zhang, Xuhui Huang, Shawn S.C. Li, Guoping Feng, Youming Lu, Mingjie Zhang
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Cell Reports
Subjects:
GK domain
PSD-95
SAPAP
MAGUK
postsynaptic density
synaptic scaffold proteins
synaptogenesis
synaptic plasticity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717317916

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http://www.sciencedirect.com/science/article/pii/S2211124717317916

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