Asthma and elevation of anti-citrullinated protein antibodies prior to the onset of rheumatoid arthritis

Asthma and elevation of anti-citrullinated protein antibodies prior to the onset of rheumatoid arthritis

Abstract Background Anti-citrullinated protein antibodies (ACPA) are central to rheumatoid arthritis (RA) pathogenesis and may develop at inflamed mucosa. We investigated whether asthma, a disease of airway mucosal inflammation, was associated with elevated ACPA before RA diagnosis. Methods We perfo...

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Bibliographic Details
Main Authors: Alessandra Zaccardelli, Xinyi Liu, Julia A. Ford, Jing Cui, Bing Lu, Su H. Chu, Peter H. Schur, Cameron B. Speyer, Karen H. Costenbader, William H. Robinson, Jeremy Sokolove, Elizabeth W. Karlson, Carlos A. Camargo, Jeffrey A. Sparks
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Arthritis Research & Therapy
Subjects:
Asthma
Anti-citrullinated protein antibody
Rheumatoid arthritis
Pathogenesis
Online Access:http://link.springer.com/article/10.1186/s13075-019-2035-3

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http://link.springer.com/article/10.1186/s13075-019-2035-3

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