Emerging per- and polyfluoroalkyl substance perfluoro-(3,5,7,9-tetraoxadecanoic) acid (PFO4DA) impairs steroidogenesis and spermatogenesis by suppressing StAR and CYP11A1 expression in mice

Emerging per- and polyfluoroalkyl substance perfluoro-(3,5,7,9-tetraoxadecanoic) acid (PFO4DA) impairs steroidogenesis and spermatogenesis by suppressing StAR and CYP11A1 expression in mice

Perfluoroalkyl ether carboxylic acids (PFECA) represent an important group of emerging per- and polyfluoroalkyl substances (PFAS). PFECA have been found in a variety of environmental matrices. While legacy PFAS have been extensively documented for their reproductive toxicity, the health implications...

Full description

Bibliographic Details
Main Authors: Lutefei Mutalifu, Wei Xie, Danyang Wang, Mengxue Zhi, Yong Guo, Jianshe Wang
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PFO4DA
Leydig cell
Testosterone
Steroidogenesis
Blood-testis barrier
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325002982

Internet

http://www.sciencedirect.com/science/article/pii/S0147651325002982

Similar Items