The Neutralizing Antibody Response Elicited by Tembusu Virus Is Affected Dramatically by a Single Mutation in the Stem Region of the Envelope Protein

The Neutralizing Antibody Response Elicited by Tembusu Virus Is Affected Dramatically by a Single Mutation in the Stem Region of the Envelope Protein

Tembusu virus (TMUV) is a mosquito-borne flavivirus that most commonly affects adult breeder and layer ducks. However, a TMUV-caused neurological disease has also been found in ducklings below 7 weeks of age, highlighting the need to develop a safe vaccine for young ducklings. In this study, a plaqu...

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Bibliographic Details
Main Authors: Junfeng Lv, Xiaoxiao Liu, Shulin Cui, Lixin Yang, Shenghua Qu, Runze Meng, Baolin Yang, Chonglun Feng, Xiaoyan Wang, Dabing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Microbiology
Subjects:
duck
Tembusu virus
attenuation
neutralizing antibody
envelope protein
stem region
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.585194/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.585194/full

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