Gut microbiota involved in desulfation of sulfated progesterone metabolites: A potential regulation pathway of maternal bile acid homeostasis during pregnancy

Gut microbiota involved in desulfation of sulfated progesterone metabolites: A potential regulation pathway of maternal bile acid homeostasis during pregnancy

Abnormally raised circulating bile acids (BA) during pregnancy threat fetal and offspring health. Our previous study has identified sulfated progesterone metabolites (PMSs) in part account for dysregulation of maternal BA homeostasis during pregnancy, however, limited intervention strategies to reme...

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Bibliographic Details
Main Authors: Peng Wang, Qianqian Chen, Peiqiang Yuan, Sen Lin, Hong Chen, Ran Li, Xiaoling Zhang, Yong Zhuo, Jian Li, Lianqiang Che, Bin Feng, Yan Lin, Shengyu Xu, De Wu, Zhengfeng Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Microbiology
Subjects:
bile acid homeostasis
pregnant sows
gut microbiota
vancomycin
sulfated progesterone metabolites
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1023623/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.1023623/full

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