SENP1 regulates the transformation of lung resident mesenchymal stem cells and is associated with idiopathic pulmonary fibrosis progression

SENP1 regulates the transformation of lung resident mesenchymal stem cells and is associated with idiopathic pulmonary fibrosis progression

Abstract Background Lung resident mesenchymal stem cells (LR-MSCs) play an important role in idiopathic pulmonary fibrosis (IPF) by transforming into myofibroblasts, thereby losing their repair ability. Evidence suggests that key proteins of multiple signaling pathways are involved in myofibroblast...

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Bibliographic Details
Main Authors: Wei Sun, Xiaoshu Liu, Xiaoyu Yang, Xiaoyan Jing, Chunyan Duan, Ganghao Yang, Chi Wu, Hui Huang, Qun Luo, Shu Xia, Qian Zhang, Yang Yang, Zuojun Xu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cell Communication and Signaling
Subjects:
Idiopathic pulmonary fibrosis
Myofibroblasts
Lung resident mesenchymal stem cells
SENP1
Online Access:https://doi.org/10.1186/s12964-022-00921-4

Internet

https://doi.org/10.1186/s12964-022-00921-4

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