Discrimination of Carcinogens by Hepatic Transcript Profiling in Rats following 28-day Administration

This study aimed at discriminating carcinogens on the basis of hepatic transcript profiling in the rats administrated with a variety of carcinogens and non-carcinogens. We conducted 28-day toxicity tests in male F344 rats with 47 carcinogens and 26 non-carcinogens, and then investigated periodically...

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Bibliographic Details
Main Authors: Hiroshi Matsumoto, Yoshikuni Yakabe, Koichi Saito, Kayo Sumida, Masaru Sekijima, Koji Nakayama, Hideki Miyaura, Fumiyo Saito, Masanori Otsuka, Tomoyuki Shirai
Format: Article
Language:English
Published: SAGE Publishing 2009-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S3229