Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients

Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients

Abstract Background Circulating cell-free miRNAs have emerged as promising minimally-invasive biomarkers for early detection, prognosis and monitoring of cancer. They can exist in the bloodstream incorporated into extracellular vesicles (EVs) and ribonucleoprotein complexes. However, it is still deb...

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Bibliographic Details
Main Authors: Edgars Endzeliņš, Andreas Berger, Vita Melne, Cristina Bajo-Santos, Kristīne Soboļevska, Artūrs Ābols, Marta Rodriguez, Daiga Šantare, Anastasija Rudņickiha, Vilnis Lietuvietis, Alicia Llorente, Aija Linē
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Cancer
Subjects:
Prostate cancer
Cell-free miRNAs
Extracellular vesicles
Exosomes
Microvesicles
Biomarkers
Online Access:http://link.springer.com/article/10.1186/s12885-017-3737-z

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http://link.springer.com/article/10.1186/s12885-017-3737-z

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