Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death

Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death

Multidrug resistance (MDR) is a major challenge in cancer chemotherapy. Nanoparticles as drug delivery systems (DDSs) show promise for MDR cancer therapy. However, current DDSs require sophisticated design and construction based on xenogeneic nanomaterials, evoking feasibility and biocompatibility c...

Full description

Bibliographic Details
Main Authors: Chih-Peng Lin, Shu-Hui Wu, Tzu-Yin Lin, Chia-Hui Chu, Leu-Wei Lo, Ching-Chuan Kuo, Jang-Yang Chang, Szu-Chun Hsu, Bor-Sheng Ko, Ming Yao, Jong-Kai Hsiao, Shih-Wei Wang, Dong-Ming Huang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Pharmacological Research
Subjects:
Multidrug resistance
Drug delivery
Nanoparticle
RBC
Cancer chemotherapy
Doxorubicin
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823003018

Internet

http://www.sciencedirect.com/science/article/pii/S1043661823003018

Similar Items