A Review on DNA Repair Inhibition by PARP Inhibitors in Cancer Therapy
The DNA repair process protects the cells from DNA damaging agent by multiple pathways. Majority of the cancer therapy cause DNA damage which leads to apoptosis. The cell has natural ability to repair this damage which ultimately leads to development of resistance of drugs. The key enzymes involved...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pensoft Publishers
2018-03-01
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| Series: | Folia Medica |
| Subjects: | |
| Online Access: | http://www.degruyter.com/view/j/folmed.2017.60.issue-1/folmed-2017-0067/folmed-2017-0067.xml?format=INT |