Efficacy of nonviral gene transfer of human hepatocyte growth factor (HGF) against ischemic-reperfusion nerve injury in rats.

Efficacy of nonviral gene transfer of human hepatocyte growth factor (HGF) against ischemic-reperfusion nerve injury in rats.

Ischemic neuropathy is common in subjects with critical limb ischemia, frequently causing chronic neuropathic pain. However, neuropathic pain caused by ischemia is hard to control despite the restoration of an adequate blood flow. Here, we used a rat model of ischemic-reperfusion nerve injury (IRI)...

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Bibliographic Details
Main Authors: Toyokazu Tsuchihara, Hitoshi Nukada, Kuniaki Nakanishi, Ryuichi Morishita, Masatoshi Amako, Hiroshi Arino, Koichi Nemoto, Kazuhiro Chiba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0237156

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https://doi.org/10.1371/journal.pone.0237156

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