Naringenin and β-carotene convert human white adipocytes to a beige phenotype and elevate hormone- stimulated lipolysis

Naringenin and β-carotene convert human white adipocytes to a beige phenotype and elevate hormone- stimulated lipolysis

IntroductionNaringenin, a peroxisome proliferator-activated receptor (PPAR) activator found in citrus fruits, upregulates markers of thermogenesis and insulin sensitivity in human adipose tissue. Our pharmacokinetics clinical trial demonstrated that naringenin is safe and bioavailable, and our case...

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Bibliographic Details
Main Authors: Ann A. Coulter, Frank L. Greenway, Dachuan Zhang, Sujoy Ghosh, Cathryn R. Coulter, Sarah L. James, Yanlin He, Luke A. Cusimano, Candida J. Rebello
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Endocrinology
Subjects:
UCP1
naringenin
carotenoid
PPARγ
RXRγ
PPARα
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1148954/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1148954/full

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