Incidence of therapy-related acute leukaemia in mitoxantrone-treated multiple sclerosis patients in Germany

Background: The incidence of therapy-related acute leukaemia (TRAL) in mitoxantrone treatment in multiple sclerosis (MS) is controversially discussed. Methods and results: In a retrospective meta-analysis from six centres, we observed six cases of acute myeloid leukaemia (AML) (incidence 0.41% for p...

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Bibliographic Details
Main Authors: Anke Stroet, Claudia Hemmelmann, Michaela Starck, Uwe Zettl, Jan Dörr, Friedemann Paul, Peter Flachenecker, Vinzenz Fleischer, Frauke Zipp, Holger Nückel, Bernd C Kieseier, Andreas Ziegler, Ralf Gold, Andrew Chan
Format: Article
Language:English
Published: SAGE Publishing 2012-03-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756285611433318