Giving Drugs a Second Chance: Antibacterial and Antibiofilm Effects of Ciclopirox and Ribavirin against Cystic Fibrosis <i>Pseudomonas aeruginosa</i> Strains

Giving Drugs a Second Chance: Antibacterial and Antibiofilm Effects of Ciclopirox and Ribavirin against Cystic Fibrosis <i>Pseudomonas aeruginosa</i> Strains

Drug repurposing is an attractive strategy for developing new antibacterial molecules. Herein, we evaluated the in vitro antibacterial, antibiofilm, and antivirulence activities of eight FDA-approved “non-antibiotic” drugs, comparatively to tobramycin, against selected <i>Pseudomonas aeruginos...

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Bibliographic Details
Main Authors: Giovanni Di Bonaventura, Veronica Lupetti, Simone De Fabritiis, Alessandra Piccirilli, Annamaria Porreca, Marta Di Nicola, Arianna Pompilio
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
drug repurposing
cystic fibrosis
<i>Pseudomonas aeruginosa</i>
biofilm
Online Access:https://www.mdpi.com/1422-0067/23/9/5029

Internet

https://www.mdpi.com/1422-0067/23/9/5029

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