Elevated serum levels of methylglyoxal are associated with impaired liver function in patients with liver cirrhosis

Elevated serum levels of methylglyoxal are associated with impaired liver function in patients with liver cirrhosis

Abstract Methylglyoxal (MGO) is a highly reactive dicarbonyl species that forms advanced glycation end products (AGEs). The binding of these AGEs to their receptor (RAGE) causes and sustains severe inflammation. Systemic inflammation is postulated to be a major driver in the progression of liver cir...

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Bibliographic Details
Main Authors: Maurice Michel, Cornelius Hess, Leonard Kaps, Wolfgang M. Kremer, Max Hilscher, Peter R. Galle, Markus Moehler, Jörn M. Schattenberg, Marcus-Alexander Wörns, Christian Labenz, Michael Nagel
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00119-7

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https://doi.org/10.1038/s41598-021-00119-7

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