Synergistic action between a synthetic cannabinoid compound and tramadol in neuropathic pain rats

Synergistic action between a synthetic cannabinoid compound and tramadol in neuropathic pain rats

In the present study the interaction of cannabinoid, PhAR-DBH-Me [(R, Z)-18-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-18-oxooctadec-9-en-7-ylphenyl-acetate] and tramadol in two neuropathy models, as well as their possible toxic effects, was analyzed. The anti-allodynic effect of PhAR-DBH...

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Bibliographic Details
Main Authors: Quiñonez-Bastidas Geovanna Nallely, Osuna-Martínez Ulises, Reda-Licea Ana Laura, López-Ortíz Manuel, Regla Ignacio, Navarrete Andrés
Format: Article
Language:English
Published: Sciendo 2022-12-01
Series:Acta Pharmaceutica
Subjects:
cannabinoid receptors
phar-dbh-me
tramadol
synergism
antiallodynic effect
Online Access:https://doi.org/10.2478/acph-2022-0037

Internet

https://doi.org/10.2478/acph-2022-0037

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