Renal function declines more in tenofovir- than abacavir-based antiretroviral therapy in low-body weight treatment-naïve patients with HIV infection.

OBJECTIVE: To compare the rate of decline of renal function in tenofovir- and abacavir-based antiretroviral therapy (ART) in low-body weight treatment-naïve patients with HIV infection. DESIGN: We conducted a single-center retrospective cohort study of 503 Japanese patients who commenced on either t...

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Bibliographic Details
Main Authors: Takeshi Nishijima, Hiroyuki Gatanaga, Hirokazu Komatsu, Kunihisa Tsukada, Takuro Shimbo, Takahiro Aoki, Koji Watanabe, Ei Kinai, Haruhito Honda, Junko Tanuma, Hirohisa Yazaki, Miwako Honda, Katsuji Teruya, Yoshimi Kikuchi, Shinichi Oka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3252345?pdf=render