SGLT1 Inhibition Attenuates Apoptosis in Diabetic Cardiomyopathy via the JNK and p38 Pathway

SGLT1 Inhibition Attenuates Apoptosis in Diabetic Cardiomyopathy via the JNK and p38 Pathway

Background: Recent studies have revealed that a novel selective sodium-glucose cotransporter 1 (SGLT1) inhibiton has shown beneficial effects in cardiovascular diseases. However, the question of whether SGLT1 inhibition influences diabetic cardiomyopathy (DCM) remains unanswered. In this study, we i...

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Bibliographic Details
Main Authors: Na Lin, Hui Lin, Qi Yang, Wenqiang Lu, Zhenzhu Sun, Shimin Sun, Liping Meng, Jufang Chi, Hangyuan Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
SGLT1
apoptosis
diabetic cardiomyopathy
H9C2
DCM
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.598353/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.598353/full

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