IDH1 mutation is detectable in plasma cell-free DNA and is associated with survival outcome in glioma patients

IDH1 mutation is detectable in plasma cell-free DNA and is associated with survival outcome in glioma patients

Abstract Background Circulating cell-free DNA (cfDNA, liquid biopsy) is a powerful tool to detect molecular alterations. However, depending on tumor characteristics, biology and anatomic localization, cfDNA detection and analysis may be challenging. Gliomas are enclosed into an anatomic sanctuary, w...

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Bibliographic Details
Main Authors: Stefania Crucitta, Francesco Pasqualetti, Alessandra Gonnelli, Martina Ruglioni, Giovanna Irene Luculli, Martina Cantarella, Valerio Ortenzi, Cristian Scatena, Fabiola Paiar, Antonio Giuseppe Naccarato, Romano Danesi, Marzia Del Re
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
Liquid biopsy
cfDNA
IDH1
Glioma
Online Access:https://doi.org/10.1186/s12885-023-11726-0

Internet

https://doi.org/10.1186/s12885-023-11726-0

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