Proline Dehydrogenase (PRODH) Is Expressed in Lung Adenocarcinoma and Modulates Cell Survival and 3D Growth by Inducing Cellular Senescence

Proline Dehydrogenase (PRODH) Is Expressed in Lung Adenocarcinoma and Modulates Cell Survival and 3D Growth by Inducing Cellular Senescence

The identification of markers for early diagnosis, prognosis, and improvement of therapeutic options represents an unmet clinical need to increase survival in Non-Small Cell Lung Cancer (NSCLC), a neoplasm still characterized by very high incidence and mortality. Here, we investigated whether prolin...

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Bibliographic Details
Main Authors: Sarah Grossi, Elena Berno, Priscilla Chiofalo, Anna Maria Chiaravalli, Raffaella Cinquetti, Antonino Bruno, Maria Teresa Palano, Matteo Gallazzi, Stefano La Rosa, Fausto Sessa, Francesco Acquati, Paola Campomenosi
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
proline dehydrogenase
lung cancer
immunohistochemical analysis
adenocarcinoma cell lines
cell-based assays
cellular senescence
Online Access:https://www.mdpi.com/1422-0067/25/2/714

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https://www.mdpi.com/1422-0067/25/2/714

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