Key LncRNAs Associated With Oxidative Stress Were Identified by GEO Database Data and Whole Blood Analysis of Intervertebral Disc Degeneration Patients

Key LncRNAs Associated With Oxidative Stress Were Identified by GEO Database Data and Whole Blood Analysis of Intervertebral Disc Degeneration Patients

Background: Intervertebral disc degeneration (IDD) is a major cause of low back pain, but the onset and progression of IDD are unknown. Long non-coding RNA (lncRNA) has been validated to play a critical role in IDD, while an increasing number of studies have linked oxidative stress (OS) to the initi...

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Bibliographic Details
Main Authors: Xueliang Jiang, Junfei Wu, Chunhui Guo, Wenhui Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genetics
Subjects:
intervertebral disc degeneration (IDD)
long noncoding RNA (lncRNA)
oxidative stress (OS)
competing endogenous RNA (CeRNA)
immune landscape
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.929843/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.929843/full

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