Polycomb repressor complex: Its function in human cancer and therapeutic target strategy

Polycomb repressor complex: Its function in human cancer and therapeutic target strategy

The Polycomb Repressor Complex (PRC) plays a pivotal role in gene regulation during development and disease, with dysregulation contributing significantly to various human cancers. The intricate interplay between PRC and cellular signaling pathways sheds light on cancer complexity. PRC presents prom...

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Bibliographic Details
Main Authors: Jingrong Liu, Hongjie Fan, Xinmiao Liang, Yang Chen
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Polycomb repressor complex
Epigenetic modification
Tumorigenesis
Cancer progression
Therapeutic target
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223016955

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http://www.sciencedirect.com/science/article/pii/S0753332223016955

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