Efficient Combination of Complex Chromatography, Molecular Docking and Enzyme Kinetics for Exploration of Acetylcholinesterase Inhibitors from <i>Poria cocos</i>

Efficient Combination of Complex Chromatography, Molecular Docking and Enzyme Kinetics for Exploration of Acetylcholinesterase Inhibitors from <i>Poria cocos</i>

<i>Poria cocos (P. cocos)</i> is a traditional Chinese medicinal product with the same origin as medicine and food. It has diuretic, anti-inflammatory and liver protection properties, and has been widely used in a Chinese medicine in the treatment of Alzheimer’s disease (AD). This study...

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Bibliographic Details
Main Authors: Tong Wu, Wanchao Hou, Chunming Liu, Sainan Li, Yuchi Zhang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
<i>Poria cocos</i>
acetylcholinesterase inhibitors
molecular docking technique
enzymatic reactions kinetics
counter-current chromatography
semi-preparative high−performance liquid chromatography
Online Access:https://www.mdpi.com/1420-3049/28/3/1228

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https://www.mdpi.com/1420-3049/28/3/1228

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