Whole-Genome Sequencing of 502 Individuals from Latvia: The First Step towards a Population-Specific Reference of Genetic Variation

Whole-Genome Sequencing of 502 Individuals from Latvia: The First Step towards a Population-Specific Reference of Genetic Variation

Despite rapid improvements in the accessibility of whole-genome sequencing (WGS), understanding the extent of human genetic variation is limited by the scarce availability of genome sequences from underrepresented populations. Developing the population-scale reference database of Latvian genetic var...

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Bibliographic Details
Main Authors: Raimonds Reščenko, Monta Brīvība, Ivanna Atava, Vita Rovīte, Raitis Pečulis, Ivars Silamiķelis, Laura Ansone, Kaspars Megnis, Līga Birzniece, Mārcis Leja, Liqin Xu, Xulian Shi, Yan Zhou, Andis Slaitas, Yong Hou, Jānis Kloviņš
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
whole-genome sequencing
genetic variation
population-specific reference panel
imputation performance
Latvian genomes
Online Access:https://www.mdpi.com/1422-0067/24/20/15345

Internet

https://www.mdpi.com/1422-0067/24/20/15345

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