Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size
Hematopoietic stem cells (HSCs) rely on a combination of paracrine signals produced by their niche, including SCF. Here the authors show that HSCs and hematopoietic progenitors compete for limited amounts of membrane-bound SCF.
| Autori principali: | , , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
Nature Portfolio
2022-08-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-022-32228-w |