Nrf2/HO-1 Signaling Stimulation through Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) Provides Neuroprotection in Ethidium Bromide-Induced Experimental Model of Multiple Sclerosis

Nrf2/HO-1 Signaling Stimulation through Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) Provides Neuroprotection in Ethidium Bromide-Induced Experimental Model of Multiple Sclerosis

Multiple sclerosis (MS) is a severe immune-mediated neurological disease characterized by neuroinflammation, demyelination, and axonal degeneration in the central nervous system (CNS). This is frequently linked to motor abnormalities and cognitive impairments. The pathophysiological hallmarks of MS...

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Bibliographic Details
Main Authors: Shubham Upadhayay, Sidharth Mehan, Aradhana Prajapati, Pranshul Sethi, Manisha Suri, Ayat Zawawi, Majed N. Almashjary, Shams Tabrez
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Genes
Subjects:
multiple sclerosis
Nrf2/HO-1
acetyl-11-keto-beta-boswellic acid (AKBA)
demyelination
ethidium bromide (Etb)
neurodegeneration
Online Access:https://www.mdpi.com/2073-4425/13/8/1324

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https://www.mdpi.com/2073-4425/13/8/1324

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