Safety and immunogenicity of a live oral recombinant cholera vaccine VA1.4: a randomized, placebo controlled trial in healthy adults in a cholera endemic area in Kolkata, India.

Safety and immunogenicity of a live oral recombinant cholera vaccine VA1.4: a randomized, placebo controlled trial in healthy adults in a cholera endemic area in Kolkata, India.

BACKGROUND: A live oral cholera vaccine VA 1.4 developed from a non-toxigenic Vibrio cholerae O1 El Tor strain using ctxB gene insertion was further developed into a clinical product following cGMP and was evaluated in a double-blind randomized placebo controlled parallel group two arm trial with al...

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Bibliographic Details
Main Authors: Suman Kanungo, Bandana Sen, Thandavarayan Ramamurthy, Dipika Sur, Byomkesh Manna, Gururaja P Pazhani, Goutam Chowdhury, Puja Jhunjhunwala, Ranjan K Nandy, Hemanta Koley, Mihir Kumar Bhattacharya, Sanjay Gupta, Gaurav Goel, Bindu Dey, Thungapathra M, G Balakrish Nair, Amit Ghosh, Dilip Mahalanabis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4077646?pdf=render

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http://europepmc.org/articles/PMC4077646?pdf=render

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