Cannabinoids alleviate experimentally induced intestinal inflammation by acting at central and peripheral receptors.

In an attempt to further investigate the role of cannabinoid (CB) system in the pathogenesis of inflammatory bowel diseases, we employed two recently developed ligands, AM841 (a covalently acting CB agonist) and CB13 (a peripherally-restricted CB agonist) to establish whether central and peripheral...

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Bibliographic Details
Main Authors: Jakub Fichna, Misha Bawa, Ganesh A Thakur, Ritesh Tichkule, Alexandros Makriyannis, Donna-Marie McCafferty, Keith A Sharkey, Martin Storr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4183544?pdf=render