Characterizing Phage-Host Interactions in a Simplified Human Intestinal Barrier Model

Characterizing Phage-Host Interactions in a Simplified Human Intestinal Barrier Model

An intestinal epithelium model able to produce mucus was developed to provide an environment suitable for testing the therapeutic activity of gut bacteriophages. We show that <i>Enterococcus faecalis</i> adheres more effectively in the presence of mucus, can invade the intestinal epithel...

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Bibliographic Details
Main Authors: María A. Núñez-Sánchez, Joan Colom, Lauren Walsh, Colin Buttimer, Andrei Sorin Bolocan, Rory Pang, Cormac G. M. Gahan, Colin Hill
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Microorganisms
Subjects:
<i>Enterococcus faecalis</i>
bacteriophage
<i>Herelleviridae</i>
intestinal model
phage therapy
IBD
Online Access:https://www.mdpi.com/2076-2607/8/9/1374

Internet

https://www.mdpi.com/2076-2607/8/9/1374

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