Dickkopf‐1 drives perineural invasion via PI3K–AKT signaling pathway in head and neck squamous cancer

Dickkopf‐1 drives perineural invasion via PI3K–AKT signaling pathway in head and neck squamous cancer

Abstract Perineural invasion (PNI) leads to the poor prognosis of head and neck squamous cancer (HNSCC) patients, but the mechanism of PNI remains unclear. Dickkopf‐1 (DKK1), a secretory protein in the Wnt signaling pathway, was found indeed upregulated in HNSCC cells and tissues. Higher expression...

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Bibliographic Details
Main Authors: Jingyi Wang, Qianying Li, Faya Liang, Xin Du, Pan Song, Taowei Wu, Renhui Chen, Xiaorong Lin, Qinglian Liu, Hai Hu, Ping Han, Xiaoming Huang
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:MedComm
Subjects:
AKT
Dickkopf 1
head and neck squamous cell carcinoma
perineural invasion
Online Access:https://doi.org/10.1002/mco2.518

Internet

https://doi.org/10.1002/mco2.518

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