Administration methods and dosage of poly(lactic acid)-glycol intervention to myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalitis mice

Abstract Background Myelin oligodendrocyte glycoprotein-associated disorders (MOGAD) is an autoimmune central nervous system disease. Antigen-specific immune tolerance using nanoparticles such as Polylactic-co-glycolic acid (PLGA) have recently been used as a new therapeutic tolerization approach fo...

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Bibliographic Details
Main Authors: Amy E. Wright, Shuhei Nishiyama, Patrick Han, Philip Kong, Michael Levy
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Neuroscience
Subjects:
Online Access:https://doi.org/10.1186/s12868-024-00859-y