Downregulated DUXAP8 lncRNA impedes trophoblast cell proliferation and migration by epigenetically upregulating TFPI2 expression

Abstract Background Preeclampsia (PE), a pregnancy complication characterized by new-onset hypertension and proteinuria during the second trimester, is the leading cause of neonatal and maternal morbidity and mortality. In the etiology of PE, failure of uterine spiral artery remodeling may be relate...

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Bibliographic Details
Main Authors: Xiaotong Tang, Yueying Cao, Dan Wu, Lizhou Sun, Yetao Xu
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:https://doi.org/10.1186/s12958-023-01108-3