Downregulated DUXAP8 lncRNA impedes trophoblast cell proliferation and migration by epigenetically upregulating TFPI2 expression
Abstract Background Preeclampsia (PE), a pregnancy complication characterized by new-onset hypertension and proteinuria during the second trimester, is the leading cause of neonatal and maternal morbidity and mortality. In the etiology of PE, failure of uterine spiral artery remodeling may be relate...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-06-01
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Series: | Reproductive Biology and Endocrinology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12958-023-01108-3 |