Na<sup>+</sup>/K<sup>+</sup>-ATPase Alpha 2 Isoform Elicits Rac1-Dependent Oxidative Stress and TLR4-Induced Inflammation in the Hypothalamic Paraventricular Nucleus in High Salt-Induced Hypertension

Na<sup>+</sup>/K<sup>+</sup>-ATPase Alpha 2 Isoform Elicits Rac1-Dependent Oxidative Stress and TLR4-Induced Inflammation in the Hypothalamic Paraventricular Nucleus in High Salt-Induced Hypertension

Background: Numerous studies have indicated that a high salt diet inhibits brain Na<sup>+</sup>/K<sup>+</sup>-ATPase (NKA) activity, and affects oxidative stress and inflammation in the paraventricular nucleus (PVN). Furthermore, Na<sup>+</sup>/K<sup>+</s...

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Bibliographic Details
Main Authors: Qing Su, Xiao-Jing Yu, Xiao-Min Wang, Bo Peng, Juan Bai, Hong-Bao Li, Ying Li, Wen-Jie Xia, Li-Yan Fu, Kai-Li Liu, Jin-Jun Liu, Yu-Ming Kang
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Antioxidants
Subjects:
alpha 2 Na<sup>+</sup>/K<sup>+</sup>-ATPase
oxidative stress
inflammation
hypothalamic paraventricular nucleus
salt-induced hypertension
Online Access:https://www.mdpi.com/2076-3921/11/2/288

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https://www.mdpi.com/2076-3921/11/2/288

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