Pathological α-synuclein detected by real-time quaking-induced conversion in synucleinopathies

synucleinopathies are diseases characterized by the aggregation of α-synuclein (α-syn), which forms fibrils through misfolding and accumulates in a prion-like manner. To detect the presence of these α-syn aggregates in clinical samples, seed amplification assays (SAAs) have been developed. These SAA...

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Main Authors: Juan Huang, Xingxing Yuan, Lin Chen, Binbin Hu, Hui Wang, Ye Wang, Wei Huang
格式: 文件
语言:English
出版: Elsevier 2024-03-01
丛编:Experimental Gerontology
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在线阅读:http://www.sciencedirect.com/science/article/pii/S0531556524000081