Pathological α-synuclein detected by real-time quaking-induced conversion in synucleinopathies
synucleinopathies are diseases characterized by the aggregation of α-synuclein (α-syn), which forms fibrils through misfolding and accumulates in a prion-like manner. To detect the presence of these α-syn aggregates in clinical samples, seed amplification assays (SAAs) have been developed. These SAA...
Main Authors: | , , , , , , |
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格式: | 文件 |
语言: | English |
出版: |
Elsevier
2024-03-01
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丛编: | Experimental Gerontology |
主题: | |
在线阅读: | http://www.sciencedirect.com/science/article/pii/S0531556524000081 |