A Fast Multi-Locus Ridge Regression Algorithm for High-Dimensional Genome-Wide Association Studies
The mixed linear model (MLM) has been widely used in genome-wide association study (GWAS) to dissect quantitative traits in human, animal, and plant genetics. Most methodologies consider all single nucleotide polymorphism (SNP) effects as random effects under the MLM framework, which fail to detect...
Prif Awduron: | , , , , , , |
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Fformat: | Erthygl |
Iaith: | English |
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Frontiers Media S.A.
2021-03-01
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Cyfres: | Frontiers in Genetics |
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Mynediad Ar-lein: | https://www.frontiersin.org/articles/10.3389/fgene.2021.649196/full |