Zika structural genes determine the virulence of African and Asian lineages

ABSTRACTThe Asian lineage of Zika virus (ZIKV) is responsible for the recent epidemics in the Americas and severe disease, whereas the African lineage of ZIKV has not been reported to cause epidemics or severe disease. We constructed a cDNA infectious clone (IC) of an African ZIKV strain, which, tog...

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Main Authors: Bruno T. D. Nunes, Camila R. Fontes-Garfias, Chao Shan, Antonio E. Muruato, Jannyce G. C. Nunes, Rommel M. R. Burbano, Pedro F. C. Vasconcelos, Pei-Yong Shi, Daniele B. A. Medeiros
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1753583