A Farnesyltransferase Acts to Inhibit Ectopic Neurite Formation in C. elegans.

Genetic pathways that regulate nascent neurite formation play a critical role in neuronal morphogenesis. The core planar cell polarity components VANG-1/Van Gogh and PRKL-1/Prickle are involved in blocking inappropriate neurite formation in a subset of motor neurons in C. elegans. A genetic screen f...

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Bibliographic Details
Main Authors: David Carr, Leticia Sanchez-Alvarez, Janice H Imai, Cristina Slatculescu, Nathaniel Noblett, Lei Mao, Lorena Beese, Antonio Colavita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4907426?pdf=render